Medicinal Uses :Berberine, universally present in rhizomes of Mahonia species, has marked antibacterial effects and is used as a bitter tonic. Since it is not appreciably absorbed by the body, it is used orally in the treatment of various enteric infections, especially bacterial dysentery. It should not be used with Glycyrrhiza species (Liquorice) because this nullifies the effects of the berberine. Berberine has also shown antitumour activity. The root and root bark are best harvested in the autumn.
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